Best prepaid GLP-1 programs to compare: full costs and renewal terms

How this shortlist was selected

CoreAge Rx is number one because it is our featured commercial partner. That position is predetermined by our commercial relationship, and we may earn compensation through its links. Other entries illustrate relevant care and payment models; their order is not a ranking of medication quality, safety, or patient outcomes.

Write down the upfront total, exact covered period, next renewal date, and refund conditions before comparing the monthly equivalent. We used the provider documents linked beside each entry, checked September 21, 2026. We did not purchase treatment, test private accounts, audit every license, or measure response times. The product and current written quote for your own care still need confirmation. Read our review method.

01. CoreAge Rx — featured partner

Our featured partner publishes an example in which a three-month plan at a $149 monthly equivalent is charged as $447 upfront. Use the actual selected plan’s total, not that example as a universal quote.

The current sale page advertises semaglutide from $99 per month and tirzepatide from $149 per month, with no membership fee. Those are advertised starting figures, not a personalized checkout quote. The plan length and total amount due must be read alongside the monthly equivalent.

The sale page says CoreAge works with U.S. compounding pharmacies and describes 503A facilities. A category of pharmacy is not a substitute for the name, address, and state license of the pharmacy filling your own prescription. Request that information before deciding.

Continue with our CoreAge Rx review and pricing details.

02. Fifty 410

Publishes total charges for three-month tirzepatide packages and different tiers. Compare the selected package and refill plan rather than assuming the starter figure applies throughout treatment.

Fifty 410 lists a three-month compounded tirzepatide starter package at $399 total, displayed as $133 per month. The listed mid- and higher-dose packages are $499 and $549 total. Its semaglutide monthly option is $199. These are different products and package sizes.

Ask which package matches the proposed prescription and whether a returning patient qualifies for a starter offer. A three-month supply and monthly billing are separate arrangements.

Check the official Fifty 410 program page for the current offer and conditions. Our Fifty 410 alternatives comparison examines other care models.

03. Yucca Health

Provides explicit six-month totals and monthly alternatives. That lets you assess both the advertised saving and the larger immediate payment.

Yucca lists semaglutide at $125 per month on a six-month plan totaling $750, or $146 month to month. Tirzepatide is listed at $225 per month on a six-month plan totaling $1,350, or $258 month to month.

The $125 headline is a prepaid-plan equivalent, not the monthly-plan charge. Keep the selected term, renewal price, and cancellation policy with the purchase summary.

Check the official Yucca Health program page for the current offer and conditions. Our Yucca Health alternatives comparison examines other care models.

04. GobyMeds

Shows three-month starter-bundle totals with several inclusions. Ask for the nonintroductory renewal and the policy once a prescription reaches the pharmacy.

GobyMeds lists a three-month semaglutide starter bundle at $299 total and a tirzepatide starter bundle at $399 total. Its $99 and $133 monthly headlines describe those bundles; the page says the lowest figures can reflect multi-month or introductory offers.

Cancellation depends on whether the prescription has reached the pharmacy. A prepaid starter bundle is not a guarantee of the same renewal price, and HSA/FSA payment is not insurance coverage.

Check the official GobyMeds program page for the current offer and conditions.

05. Big Easy Weight Loss

Uses 12-week package language and pharmacy-specific options. Translate the 84-day period before comparing it with calendar-month programs.

Big Easy shows 12-week starting packages for compounded semaglutide and tirzepatide. Its page displays starter discounts alongside regular figures: $399 versus $495 for semaglutide, and $499 versus $599 for tirzepatide. Confirm the eligible package and pharmacy before relying on a displayed price.

Twelve weeks is 84 days, not three calendar months. Compare the exact quantity, pharmacy, ingredients, and whether the new-patient discount applies to a transfer.

Check the official Big Easy Weight Loss program page for the current offer and conditions. Our Big Easy Weight Loss alternatives comparison examines other care models.

06. Brello Health

Displays three-month-plan equivalents but describes renewal every 11 weeks. The next charge date deserves a place beside the advertised monthly figure.

Brello displays semaglutide at $133 and tirzepatide at $166 per month as three-month-plan equivalents. Its terms on the same page require a three-month minimum and describe automatic renewal every 11 weeks at the rate shown at checkout.

Read the renewal date as well as the minimum term. The FAQ describes a possible $50 professional-services deduction for qualifying cancellation requests made within 24 hours of the completed provider review; this is not an unconditional refund promise.

Check the official Brello Health program page for the current offer and conditions. Our Brello Health alternatives comparison examines other care models.

The details that decide this comparison

A starter package may have eligibility or dose limits. Ask whether the same offer applies to someone already receiving treatment.

A package’s billing period, delivery schedule, and prescribed treatment duration may differ. Get each one stated clearly.

Ask how an unfilled order, a prepared prescription, and unused medication are treated under the refund policy. Prepayment does not create a right to return dispensed medicine.

Keep the treatment distinction clear

An FDA-approved branded medicine and a compounded preparation have different regulatory status. Compounded drugs are not FDA-approved. Trials of an approved product do not prove that every compounded version has the same performance.

Ask the prescribing professional why the exact product is appropriate for you, and identify the dispensing pharmacy. A price, a website’s appearance, or a place in this list cannot establish personal suitability. Our guide to compounded drugs and FDA approval explains the distinction.

Before you make a change

Consider the amount you can pay without relying on a future refund. If financing is used, ask how the financing agreement interacts with a provider cancellation or refund.

Discuss ongoing suitability with the clinician during the plan. A long financial commitment does not establish that the same prescription should continue unchanged.